(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Basic information
Product Name:(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane
Synonyms:(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane;(2S,3R)-3-(tert-ButoxycarbonylaMino)-1,2-epoxy-4-phenylbutane;tert-butyl ((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbaMate;2-Methyl-2-propanyl {(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl}carba mate;threo-N-(Tert-Butoxy)Carbonyl D-phenylalanine epoxide;(2S,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane;Atazanavir Impurity 32;tert-butyl N-[(1R)-1-[(2S)-oxiran-2-yl]-2-phenylethyl]carbamate
CAS:156474-22-5
MF:C15H21NO3
MW:263.33
EINECS:
Product Categories:Aromatics, Chiral Reagents, Heterocycles
Mol File:156474-22-5.mol
(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Structure
(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Chemical Properties
Melting point 90-95°C
Boiling point 398.8±25.0 °C(Predicted)
density 1.118±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform, DMSO, Methanol
form Solid
pka12.19±0.46(Predicted)
color White
Safety Information
MSDS Information
(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Usage And Synthesis
Uses(2S,3R)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane is an intermediate in the synthesis of Atazanavir (A790050), a novel azapeptide HIV protease inhibitor used as an antiviral agent.
(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Preparation Products And Raw materials
Des-N-(methoxycarbonyl)-L-tert-leucine Atazanavir Trihydrochloride Atazanavir Impurity 8 Atazanavir Impurity 6 Des(benzylpyridyl) Atazanavir (3R,8S,9S,12R)-Atazanavir (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane [2-(4-BENZYLOXY-PHENYL)-1(R)-(S)OXIRANYL-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER (S)-1-(TERT-BUTOXYCARBONYL)-2,3-OXIRANYLMETHYLAMINE Atazanavir IMpurity 3 Atazanavir R,R,R,R-diastereomer tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir Atazanavir IMpurity 4 Atazanavir Sulfate Atazanavir sulfate Atazanavir Impurity 14 Atazanavir EP Impurity H (Atazanavir S,R,R,S-Diastereomer) (3S,8R,9S,12S)-3,12-Bis(1,1-diMethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylMethyl)-6-[[4-(2-pyridinyl)phenyl]Methyl]-,2,5,6,10,13-pentaazatetradecanedioic Acid 1,14-DiMethyl Ester Atazanavir D6

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